Pseudopterygium arising in a patient with multiple keloids

Area of Science:

• Ophthalmology
• Cardiology
• Genetics

Background:

• Pseudopterygium is a wing-shaped fibrovascular growth on the conjunctiva.
• Ebstein's anomaly is a congenital heart defect affecting the tricuspid valve.
• Keloids are benign fibrous tumors that arise from the skin.

Observation:

• An unusual case of mechanical globe restriction due to pseudopterygium formation after minor ocular trauma.
• The patient had a history of Ebstein's anomaly and presented with keloid scarring.

Findings:

• The pseudopterygium formation directly caused mechanical restriction of ocular motility.
• This case highlights a potential, previously undocumented association between Ebstein's anomaly, keloid predisposition, and pseudopterygium development.

Implications:

• Suggests a possible systemic predisposition to abnormal tissue growth, potentially linking cardiac and integumentary conditions.
• Underscores the importance of considering underlying systemic conditions in patients presenting with unusual ocular findings.
• May prompt further research into the genetic or molecular pathways connecting these seemingly disparate conditions.