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Updated: Aug 11, 2026

Magnetic Resonance Derived Myocardial Strain Assessment Using Feature Tracking
Published on: February 12, 2011
Prediction of subclinical left ventricular dysfunction with strain rate imaging in patients with mild to moderate
Sait Dogan1, Mustafa Aydin, Metin Gursurer
1Department of Cardiology, School of Medicine, Zonguldak Karaelmas University, Zonguldak, Turkey. smdogan@yahoo.com
Background:
Left ventricular (LV) long-axis function evaluated by Doppler tissue echocardiography-derived strain rate (SR) imaging has been shown to be a useful index of LV systolic function; however, it has not been evaluated in patients with mitral stenosis (MS). We examined the LV long-axis function of patients with pure MS and normal global systolic function as assessed by LV ejection fraction.
Method:
In all, 30 patients (22 women; 45 +/- 9 years) with mild to moderate MS (mitral valve area = 1.5 +/- 0.3 cm2) and 28 healthy volunteers (20 women; 44 +/- 10 years) were evaluated by both conventional and Doppler tissue echocardiography. Two-dimensional Doppler tissue echocardiography was performed in the apical 4-chamber view in the septal and lateral wall on the mitral annular level. Peak systolic myocardial SR and end-systolic strain data were measured for both segments.
Results:
Peak systolic SR (1.2 +/- 0.4% vs 1.8 +/- 0.39%, P < .001) and end-systolic strain (10 +/- 5 vs 25 +/- 6 s(-1), P < .001) were both significantly lower in patients with MS than in control subjects.
Conclusions:
Patients with MS had significantly impaired long-axis function evaluated by Doppler tissue echocardiography-derived SR imaging despite normal global systolic function.
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