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Updated: Aug 10, 2026

Protocol for Plasmodium falciparum Infections in Mosquitoes and Infection Phenotype Determination
Published on: July 4, 2007
Problem pathogens: prevention of malaria in travellers
Carlos Franco-Paredes1, José Ignacio Santos-Preciado
1Department of Medicine, Division of Infectious Diseases, Emory University School of Medicine, Atlanta, GA, USA. cfranco@sph.emory.edu
Malaria, a significant parasitic infection, is increasingly reported in travelers due to global travel. Risk-benefit analysis of antimalarial prophylaxis is crucial for individuals visiting malaria-endemic regions.
Area of Science:
- * Global health
- * Infectious diseases
- * Parasitology
Background:
- * Malaria, caused by Plasmodium parasites, is a major global health concern with incalculable impact.
- * Historically significant, malaria continues to affect human populations worldwide.
- * Imported malaria cases are rising globally due to increased international travel.
Purpose of the Study:
- * To highlight the growing issue of imported malaria in travelers.
- * To emphasize the importance of malaria prevention strategies for travelers.
- * To discuss the challenges and considerations for antimalarial chemoprophylaxis.
Main Methods:
- * Review of current trends in imported malaria cases.
- * Analysis of factors contributing to increased malaria transmission in endemic areas.
- * Evaluation of chemoprophylaxis adherence and side effects.
Main Results:
- * International travel is a significant factor in the global spread of malaria.
- * Non-adherence to malaria chemoprophylaxis is often due to drug side effects.
- * Imported malaria cases are increasingly reported worldwide.
Conclusions:
- * Travelers to malaria-risk areas require personal protective measures and chemoprophylaxis.
- * Individualized risk-benefit assessments for antimalarial prophylaxis are essential.
- * Standby self-treatment may be an alternative for select travelers; geographically specific regimens are recommended.
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