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Prevention of myopia progression with 0.05% atropine solution
Jong-Jer Lee1, Po-Chiung Fang, I-Hui Yang
1Department of Ophthalmology, Kaohsiung Chang Gung Memorial Hospital, Kaohsiung, Taiwan, Republic of China.
Summary
Low-dose atropine eye drops effectively slow myopia progression in children. This study found 0.05% atropine significantly reduced the rate of worsening nearsightedness in school-aged participants over one year.
Area of Science:
- Ophthalmology
- Pediatric Ophthalmology
- Myopia Control
Background:
- Myopia is a growing public health concern in school-aged children.
- Effective interventions are needed to slow myopia progression and prevent high myopia.
- Topical atropine has shown promise in myopia management.
Purpose of the Study:
- To evaluate the efficacy of 0.05% atropine solution in controlling myopia progression.
- To compare myopia progression rates in children treated with 0.05% atropine versus a control group.
Main Methods:
- A retrospective, case-control study involving 57 myopic children (6-12 years old).
- One group received 0.05% atropine eyedrops nightly; the control group received no treatment.
- Refractive status changes were monitored over at least one year.
Main Results:
- Children treated with 0.05% atropine showed significantly slower myopia progression (-0.28 D/year) compared to controls (-0.75 D/year).
- The atropine group had a substantially lower rate of uncontrolled myopia progression (16.7% vs. 77.8%).
- The differences in progression rates were statistically significant (P < 0.001).
Conclusions:
- Topical 0.05% atropine is an effective treatment for controlling myopia progression in most school-aged children.
- Regular nightly instillation of low-dose atropine can manage myopia over a one-year period.
- This intervention offers a viable option for reducing the progression of nearsightedness in pediatric populations.
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