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Updated: Aug 11, 2026
Modified Radical Neck Dissection for Cervical Metastasis
Published on: February 20, 2026
[Head and neck manifestations and management of Wegener's granulomatosis]
Qingming Li1, Baoquan Zhang, Peihong Peng
1Department of Otorhinolaryngology, Peking Union Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China. qingmingly@yahoo.com.cn
Objective:
To explore the characteristic and management of Wegener's granulomatosis in head and neck.
Method:
Forty-two cases with Wegener's granulomatosis were retrospectively analyzed clinical characteristics, head and neck manifestations, biopsy, ANCA test, and management were respectively recorded. Cyclophosphamide and Prednisone are the mainstay of medical therapy.
Result:
All cases presented with multiple organ systems involvement. Nasal involvement occurred most in head and neck, the occurred rate was 81.0%, the rate of first-occurred signs and symptoms was 47.6%. The diagnosis rate by biopsy was 67.6%. The total positive rate of ANCA test was 97.4%.
Conclusion:
Head and neck involvement in Wegener's granulomatosis is most common and complicated. ANCA test and biopsy are the most main means in the diagnosis of Wegener's granulomatosis. Medical therapy is the mainstay of treatment in Wegener's granulomatosis, whereas surgery is reserved for selected head and neck manifestations.
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