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Updated: Aug 11, 2026
06:35
An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis
Published on: February 8, 2019
Central serous chorioretinopathy in giant cell arteritis
Vinay A Shah1, Sandeep Randhawa, H Culver Boldt
1University of Iowa Hospitals and Clinics, Iowa City, Iowa 52242-1091, USA.
Seminars in Ophthalmology
|March 7, 2006
Summary
Giant cell arteritis patients on steroids may develop central serous chorioretinopathy, causing vision loss. Prompt diagnosis and treatment of this steroid-induced condition are crucial for better visual outcomes.
Area of Science:
- Ophthalmology
- Rheumatology
Background:
- Giant cell arteritis (GCA) is a systemic vasculitis often treated with corticosteroids.
- Corticosteroids, while effective for GCA, can have ocular side effects.
Observation:
- A 66-year-old woman with GCA developed worsening vision (20/100 OD, 20/25 OS) after starting oral prednisone.
- Clinical examination, OCT, and FA confirmed central serous chorioretinopathy (CSCR) in both eyes (OD > OS).
Findings:
- Central serous chorioretinopathy (CSCR) was diagnosed as the cause of vision loss.
- The CSCR was likely precipitated by the high-dose steroid therapy for GCA.
Implications:
- CSCR should be considered in the differential diagnosis of vision loss in GCA patients on steroids.
- Aggressive treatment of GCA with increased steroids may exacerbate steroid-induced CSCR, worsening visual prognosis.
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