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Updated: Aug 10, 2026
09:02
Percutaneous Hepatic Perfusion (PHP) with Melphalan as a Treatment for Unresectable Metastases Confined to the Liver
Published on: July 31, 2016
Palliation of malignant ascites
1Department of Radiology, Lutheran General Hospital, 1775 Dempster Avenue, Park Ridge, IL 60068, USA. stefanier@comcast.net
Gastroenterology Clinics of North America
|March 15, 2006
Summary
Managing recurrent malignant ascites is challenging. Large-volume paracentesis is common but often requires frequent procedures due to rapid fluid reaccumulation, impacting patient quality of life.
Area of Science:
- Oncology
- Gastroenterology
- Palliative Care
Background:
- Recurrent, symptomatic malignant ascites presents significant management challenges for both physicians and patients.
- Disease progression frequently leads to rapid ascites reaccumulation, necessitating frequent hospital visits for symptom control.
Purpose of the Study:
- To review and discuss various management strategies for recurrent, symptomatic malignant ascites.
- To evaluate the efficacy and limitations of different palliative techniques.
Main Methods:
- Literature review of current management options for malignant ascites.
- Analysis of established and emerging palliative interventions.
Main Results:
- Large-volume paracentesis is the most common low-risk approach but offers temporary relief.
- Alternative methods like tunneled drainage catheters, peritoneal ports, and peritoneovenous shunts aim for more sustained symptom palliation.
Conclusions:
- Effective management of malignant ascites requires tailored strategies balancing symptom control and patient quality of life.
- Further research into optimal palliative techniques is warranted to improve patient outcomes.
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