Related Experiment Video
Updated: Aug 10, 2026

10:19
Substernal Thyroid Biopsy Using Endobronchial Ultrasound-guided Transbronchial Needle Aspiration
Published on: November 10, 2014
Angled forceps used for transbronchial biopsy in which standard forceps are difficult to manipulate: a comparative
Shinji Sasada1, Yoshitaka Ogata, Masashi Kobayashi
1Department of Thoracic Malignancy, Osaka Prefectural Medical Center for Respiratory and Allergic Disease, 3-7-1 Habikino, Habikino-Shi, Osaka 583-8588, Japan. s-sasada@hbk.pref.osaka.jp
Chest
|March 16, 2006
Summary
The Sasada transbronchial angled forceps (STAF) significantly improves diagnostic yield for peripheral pulmonary lesions (PPLs) compared to standard forceps. This novel tool enhances tissue sampling for accurate histologic diagnosis in challenging cases.
Area of Science:
- Pulmonology
- Interventional Pulmonology
- Diagnostic Bronchoscopy
Background:
- Peripheral pulmonary lesions (PPLs) pose diagnostic challenges due to their location.
- Standard forceps have limitations in accessing and obtaining adequate tissue samples from PPLs.
- The development of specialized tools is crucial for improving diagnostic yield in PPLs.
Observation:
- The Sasada transbronchial angled forceps (STAF) is a novel instrument designed with an angled tip for improved manipulation.
- A retrospective study evaluated 110 patients with PPLs, comparing STAF to standard forceps.
- Histological analysis of specimens was performed to assess diagnostic yield.
Findings:
- STAF demonstrated a significantly higher overall diagnostic yield (78.2%) compared to standard forceps (39.1%) for PPLs (p < 0.001).
- This improvement was observed for both malignant (STAF 83.3% vs. standard 44.4%) and benign lesions (STAF 68.4% vs. standard 28.9%).
- STAF showed particular efficacy in the upper lobes, though diagnostic yield was comparable for lesions <= 10 mm.
Implications:
- The STAF is a valuable tool for obtaining sufficient specimens for histologic diagnosis from difficult-to-reach PPLs.
- Its use can lead to more accurate and timely diagnoses of pulmonary conditions.
- Further research may explore STAF's utility in various PPL subtypes and patient populations.
