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Related Experiment Videos

Warfarin and royal jelly interaction.

Nancy J Lee1, Joli D Fermo

  • 1Department of Pharmacy and Clinical Sciences, South Carolina College of Pharmacy, Charleston, South Carolina 29425, USA.

Pharmacotherapy
|March 24, 2006
PubMed
Summary
This summary is machine-generated.

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An elderly patient on warfarin experienced elevated international normalized ratio (INR) and bleeding after taking royal jelly. This highlights a potential drug interaction between royal jelly and warfarin, emphasizing the need for patient education on herbal supplements.

Area of Science:

  • Pharmacology
  • Herbal Medicine Interactions

Background:

  • A patient with follicular non-Hodgkin's lymphoma and atrial fibrillation was managed with warfarin for anticoagulation.
  • His international normalized ratio (INR) was stable within the therapeutic range (2-3) prior to the event.

Observation:

  • The patient presented with hematuria and significantly elevated INR (6.88-7.29).
  • He initially denied any changes in medications or diet but later admitted to starting royal jelly one week prior.

Findings:

  • A potential drug interaction between royal jelly and warfarin is the most probable cause for the elevated INR and bleeding.
  • No prior case reports document the concomitant use of royal jelly and warfarin.

Implications:

  • Clinicians must educate patients about the potential risks of combining herbal supplements with conventional medications.

Related Experiment Videos

  • Proactive patient counseling is crucial to prevent adverse events related to dietary supplements and drug interactions.