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Related Experiment Video

Updated: Aug 13, 2025

Temporomandibular Joint Pain Measurement by Bite Force and Von Frey Filament Assays in Mice
06:37

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Temporomandibular Disorders: Rapid Evidence Review.

Eric M Matheson1, Joli D Fermo2, Russell S Blackwelder1

  • 1Medical University of South Carolina, Charleston, South Carolina.

American Family Physician
|January 23, 2023
PubMed
Summary
This summary is machine-generated.

Temporomandibular disorders (TMDs) affect millions, causing jaw pain, headaches, and clicking. Diagnosis relies on history and exam, with imaging for uncertainty, and treatment ranges from conservative to surgical.

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Area of Science:

  • Dentistry
  • Orthodontics
  • Neurology

Background:

  • Temporomandibular disorders (TMDs) affect 5-12% of the population.
  • Symptoms include headache, bruxism, jaw joint pain, clicking, neck pain, tinnitus, dizziness, hearing changes, and sound hyperacuity.
  • Physical signs involve muscle tenderness (pterygoid, temporalis), temporomandibular joints, jaw malocclusion, and crepitus.

Purpose of the Study:

  • To provide a comprehensive overview of temporomandibular disorders.
  • To outline diagnostic criteria and imaging recommendations.
  • To review current therapeutic strategies for TMDs.

Main Methods:

  • Diagnosis based on patient history and physical examination.
  • Imaging (CT, MRI) utilized when diagnosis is uncertain.
  • Review of nonpharmacologic, pharmacologic, and interventional therapies.

Main Results:

  • Nonpharmacologic treatments include patient education, cognitive behavioral therapy, and physical therapy.
  • Pharmacologic options encompass NSAIDs, cyclobenzaprine, tricyclic antidepressants, and gabapentin.
  • Injections (sodium hyaluronate, PRP, dextrose prolotherapy) show weak evidence of benefit.

Conclusions:

  • TMD diagnosis relies on clinical assessment, supplemented by imaging if needed.
  • A multimodal treatment approach is often necessary.
  • Oral and maxillofacial surgery referral is reserved for refractory cases.