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Extramammary Paget's disease and prostatic carcinoma
K J Gudmundsen1, J M Smith, P A Dervan
1Department of Dermatology, Mater Misericordiae Hospital, Dublin, Ireland.
The Australasian Journal of Dermatology
|January 1, 1991
Summary
This case study presents perianal extramammary Paget's disease (EMPD) occurring with prostate cancer. It highlights the importance of searching for internal malignancies in patients diagnosed with EMPD.
Area of Science:
- Oncology
- Dermatology
- Urology
Background:
- Extramammary Paget's disease (EMPD) is a rare intraepithelial adenocarcinoma.
- It commonly affects the anogenital region, often associated with underlying malignancies.
Observation:
- A case of simultaneous perianal extramammary Paget's disease and prostatic adenocarcinoma is detailed.
- Four prior cases of genital EMPD with prostate carcinoma are reviewed.
Findings:
- Immunohistologic techniques can aid in diagnosing EMPD.
- EMPD is linked to adenocarcinomas of sweat glands and lower urinary/gastrointestinal tracts.
Implications:
- A thorough search for internal malignancy is crucial in patients with EMPD.
- This underscores the importance of a multidisciplinary approach in managing EMPD and associated cancers.