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Chemical-Induced Skin Carcinogenesis Model Using Dimethylbenz[a]Anthracene and 12-O-Tetradecanoyl Phorbol-13-Acetate (DMBA-TPA)
Published on: December 19, 2019
Actinic keratosis and capecitabine therapy
Gerald M Higa1, Rodney F Kovach, Jame Abraham
1Department of Medicine, Section of Hematology/Oncology, West Virginia University, Morgantown, USA. ghiga@hsc.wvu.edu
Abstract:
Topical application of 5-fluorouracil (5-FU) is one of the most effective clinical strategies available to treat actinic keratosis (AK). During treatment, an apparent toxic skin reaction occurs before dermal quiescence ensues. We report a case of a typical flare of AK in a woman treated with capecitabine for advanced breast cancer.
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