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Updated: Aug 9, 2026

Optical Coherence Tomography: Imaging Mouse Retinal Ganglion Cells In Vivo
Published on: September 22, 2017
Atopic optic neuritis
C S Constantinescu1, M Thomas, A G Zaman
1Department of Neurology, University Hospital, Queen's Medical Centre, Nottingham, UK. cris.constantinescu@nottingham.ac.uk
Purpose:
To report a case of optic neuritis associated with atopic dermatitis, which may represent an optic nerve counterpart of atopic myelitis.
Methods:
Clinical examination, MRI, blood investigations.
Results:
A 34-year-old man with severe atopic dermatitis developed a steroid-responsive bilateral optic neuritis. Serum IgE was highly elevated, with high titers of mite-specific IgE. Clinical ophthalmological fluctuations paralleled those of atopic dermatitis.
Conclusions:
The clinical features and parallel fluctuations strongly suggest that the patient's optic neuritis was related to atopic dermatitis. This atopic optic neuritis may represent the optic nerve equivalent of atopic myelitis.
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