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[Increase in posterior segment depth in eyes with corneal opacities]
Ori Mahler1, Peter Hoffman, Ayala Pollack
1Department of Ophthalmology, Kaplan Medical Center, Rehovot, Israel. mahler4@netvision.net.il
Harefuah
|April 8, 2006
Summary
Children with unilateral corneal opacities experience increased eye length, particularly in the posterior segment. This elongation contributes to myopia and potential vision problems like anisometropia and amblyopia.
Area of Science:
- Ophthalmology
- Developmental Biology
Context:
- Early-onset corneal scars in animals and humans are linked to increased axial length and myopia.
- Unilateral central corneal opacification can lead to anisometropia and amblyopia due to eye elongation.
Purpose:
- To compare ocular axial length, including anterior and posterior segments, in eyes with unilateral central corneal opacification versus unaffected fellow eyes.
Summary:
- Six patients with early-onset unilateral corneal opacification underwent eye examinations and axial length measurements via A-mode ultrasound.
- Eyes with central corneal opacities showed significantly greater mean ocular length (27.53 mm vs. 23.38 mm) compared to fellow eyes.
- This increase was attributed to posterior segment elongation (19.75 mm vs. 15.87 mm), with no significant change in anterior segment length.
Impact:
- Childhood unilateral corneal opacities cause ipsilateral posterior eye segment elongation.
- The underlying cause remains unknown but may involve altered visual input.
- Progressive myopia in corneal leukoma necessitates consideration during patient follow-up and treatment.
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