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Practical asymmetric synthesis of a gamma-secretase inhibitor exploiting substrate-controlled intramolecular nitrile

Jeremy P Scott1, Steven F Oliver, Karel M J Brands

  • 1Department of Process Research, Merck Sharp & Dohme Research Laboratories, Hertford Road, Hoddesdon, Hertfordshire EN11 9BU, United Kingdom. jeremy_scott@merck.com

The Journal of Organic Chemistry
|April 8, 2006
PubMed

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