Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A biventricular ICD system with biventricular defibrillation.

Philip Spurrell1, Manish Gandhi, Christopher A Rinaldi

  • 1Derriford Hospital, Plymouth, UK.

Pacing and Clinical Electrophysiology : PACE
|April 12, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Safety Outcomes of Hybrid Open Chest Transvenous Lead Extraction: A Multicenter Experience.

Pacing and clinical electrophysiology : PACE·2025
Same author

A Primer on Gene Editing: What Does It Mean for Pathologists?

Archives of pathology & laboratory medicine·2025
Same author

Regional heterogeneity in left atrial stiffness impacts passive deformation in a cohort of patient-specific models.

PLoS computational biology·2025
Same author

Efficacy of leadless left ventricular endocardial stimulation for non-responders to cardiac resynchronization therapy.

Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing·2025
Same author

Integrating Imaging and Invasive Pressure Data into a Multiscale Whole-Heart Model.

Journal of biomechanical engineering·2025
Same author

Joint Pacing and Vascular Intervention for the Management of Cardiac Device Associated Central Venous Obstruction.

Pacing and clinical electrophysiology : PACE·2025

Managing high defibrillation thresholds (DFT) in patients with severe dilated cardiomyopathy can be challenging. This case study demonstrates successful DFT management using biventricular defibrillation with an implantable cardioverter-defibrillator (ICD) system.

Area of Science:

  • Cardiology
  • Electrophysiology
  • Medical Device Technology

Background:

  • Severe dilated cardiomyopathy often necessitates implantable cardioverter-defibrillator (ICD) implantation for sudden cardiac death prevention.
  • High defibrillation thresholds (DFT) can complicate ICD implantation, posing a risk of inadequate therapy delivery.
  • Standard defibrillation strategies may be insufficient in cases of elevated DFTs.

Observation:

  • A 59-year-old gentleman with severe dilated cardiomyopathy presented with high DFTs during ICD implantation.
  • Initial attempts to optimize DFTs using various lead configurations and coil positions were unsuccessful.
  • An inadequate defibrillation safety margin persisted despite comprehensive testing.

Findings:

  • Placement of a second lead in the coronary sinus to achieve biventricular defibrillation successfully lowered DFTs.

Related Experiment Videos

  • This strategy resulted in a satisfactory defibrillation safety margin, enabling effective therapy.
  • Biventricular defibrillation proved to be a viable solution for managing high DFTs in this complex case.

    • Implications:

    • This case highlights an effective additional strategy for managing high defibrillation thresholds in patients with dilated cardiomyopathy.
    • Biventricular defibrillation should be considered as an option even in dual-chamber biventricular ICD systems when facing high DFTs.
    • This approach may improve the safety and efficacy of ICD therapy in challenging patient populations.