Related Experiment Video

Updated: Aug 9, 2026

Modeling Brain Metastasis by Internal Carotid Artery Injection of Cancer Cells
10:01

Modeling Brain Metastasis by Internal Carotid Artery Injection of Cancer Cells

Published on: August 2, 2022

[Cerebral amyloid angiopathy presenting as a brain tumor: case report]

Gustavo Cardoso de Andrade1, Roberto Leal Silveira, Nilson Pinheiro

  • 1Serviço de Neurocirurgia, Hospital Madre Teresa, Belo Horizonte, MG, Brazil. gca@zipmail.com

Arquivos De Neuro-Psiquiatria
|April 20, 2006
PubMed

Insights

Cerebral amyloid angiopathy can mimic low-grade glioma in patients. Biopsy confirmed cerebral amyloid angiopathy, highlighting the importance of considering this in differential diagnoses.

Area of Science:

  • Neuropathology
  • Neuroradiology
  • Neuro-oncology

Background:

  • Cerebral amyloid angiopathy (CAA) is a common cause of intracerebral hemorrhage.
  • CAA can present as a mass lesion, mimicking neoplastic processes.
  • Low-grade gliomas are primary brain tumors characterized by slow growth.

Observation:

  • A 45-year-old male presented with an intracranial mass.
  • Clinical and radiological findings suggested a low-grade glioma.
  • Biopsy confirmed the diagnosis of cerebral amyloid angiopathy.

Findings:

  • The patient's presentation mimicked a low-grade glioma.
  • Histopathological examination revealed cerebral amyloid angiopathy.
  • This case underscores the diagnostic challenge posed by CAA.

Implications:

  • Accurate diagnosis of intracranial masses is crucial for appropriate management.
  • Cerebral amyloid angiopathy should be included in the differential diagnosis of glioma-like lesions.
  • Further research into atypical presentations of CAA may improve diagnostic accuracy.

More Related Videos

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery09:53

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Published on: July 5, 2021

Related Concept Videos

Brain Abscess l: Introduction01:26

Brain Abscess l: Introduction

A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial infections,...
Cerebral Edema ll: Pathophysiology01:22

Cerebral Edema ll: Pathophysiology

Vasogenic edema is a major form of cerebral edema characterized by abnormal accumulation of fluid in the brain’s extracellular space due to disruption of the blood–brain barrier (BBB). The BBB is a specialized structure composed of endothelial cells connected by tight junctions, supported by astrocytic endfeet and a basement membrane. Under normal conditions, it tightly regulates the movement of ions, proteins, and solutes between the bloodstream and brain parenchyma. When this barrier loses...
Encephalitis l: Introduction01:19

Encephalitis l: Introduction

Encephalitis is inflammation of the brain parenchyma, most often due to infections or autoimmune processes. It presents with neuropsychiatric features such as fever, altered mental status, behavioral changes, cognitive dysfunction, seizures, focal deficits, and sometimes autonomic instability. In some cases, the meninges are also involved, resulting in meningoencephalitis.Infectious CausesInfectious encephalitis is most commonly viral but can also result from bacterial, fungal, or parasitic...