Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Chronic inflammatory demyelinating polyneuropathy.

Gérard Said1

  • 1Service de Neurologie, Hôpital de Bicêtre, Assistance Publique Hopitaux de Paris, Université Paris-Sud, 94275 Le Kremlin-Bicêtre, France. gerard.said@bct.aphp.fr

Neuromuscular Disorders : NMD
|April 25, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The history of the European Neurological Society (1986-2014)-10 years later.

European journal of neurology·2024
Same author

Examination and clinical care of the patient with neuropathy.

Handbook of clinical neurology·2013
Same author

Chronic inflammatory demyelinative polyneuropathy.

Handbook of clinical neurology·2013
Same author

Vasculitic neuropathy.

Handbook of clinical neurology·2013
Same author

Sarcoidosis of the peripheral nervous system.

Handbook of clinical neurology·2013
Same author

Leprous neuropathy.

Handbook of clinical neurology·2013

Chronic inflammatory demyelinative polyneuropathy (CIDP) presents variably, often challenging diagnosis. Early recognition and treatment are crucial for managing this immune-related nerve disorder and preventing disability.

Area of Science:

  • Neurology
  • Immunology
  • Peripheral Nervous System Disorders

Background:

  • Chronic inflammatory demyelinative polyneuropathy (CIDP) is an acquired, immune-mediated peripheral neuropathy.
  • It is characterized by significant variability in clinical presentation and disease course.

Observation:

  • Typical CIDP involves progressive or relapsing motor/sensory deficits, elevated CSF protein, and demyelination on electrophysiology.
  • Atypical variants may present with predominantly motor or sensory loss, normal CSF, and non-diagnostic electrophysiological findings.

Findings:

  • Diagnostic criteria for CIDP can be challenging to meet in atypical cases, despite potential response to immunomodulatory treatments.
  • Axon loss, alongside demyelination, is a key factor contributing to disability and treatment resistance in CIDP.

Related Experiment Videos

Implications:

  • Understanding CIDP variants and diagnostic pitfalls is essential for accurate diagnosis and effective management.
  • Optimizing treatment strategies for CIDP, particularly in cases with significant axon loss, is critical for improving patient outcomes.