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Multifocal osteoma cutis in a golden retriever
Dawn M Martin1, Jan Hall, Natalie Keirstead
1Department of Clinical Studies, Ontario Veterinary College, University of Guelph. dmmartin@uoguelph.ca
Summary
A golden retriever treated for immune-mediated thrombocytopenia developed bone-forming skin tumors after corticosteroid therapy. This case highlights a rare adverse effect of prolonged steroid use in dogs.
Area of Science:
- Veterinary Medicine
- Canine Pathology
- Dermatology
Background:
- Immune-mediated thrombocytopenia is a serious condition in dogs.
- Corticosteroids are commonly used to manage immune-mediated diseases.
- Iatrogenic hyperadrenocorticism can result from prolonged corticosteroid administration.
Observation:
- A 10-year-old, obese female golden retriever was treated for immune-mediated thrombocytopenia.
- The dog received vincristine and prednisone.
- Six months after discontinuing prednisone due to suspected hyperadrenocorticism, new dermal masses appeared.
Findings:
- Histological examination revealed the dermal masses were composed of differentiated cortical bone.
- This represents a rare manifestation of bone formation in the skin.
Implications:
- This case suggests a potential link between prolonged corticosteroid therapy and the development of cutaneous ossification in dogs.
- Further research is needed to understand the mechanism and prevalence of this adverse effect.
- Veterinarians should be aware of this rare complication when managing canine patients with immune-mediated diseases requiring long-term immunosuppression.
