Controlling allergens in animal rooms by using curtains

Area of Science:

• Occupational Health and Safety
• Laboratory Animal Science
• Environmental Control

Background:

• Allergen control is crucial for staff health in animal facilities.
• Rodent allergens, such as Mus m1, pose significant occupational risks.
• Existing methods for allergen mitigation require evaluation for efficacy.

Purpose of the Study:

• To assess the effectiveness of perforated Makrolon curtains in reducing airborne allergens.
• To investigate allergen containment behind cage racks using curtains.
• To evaluate the impact of airflow dynamics on allergen distribution.

Main Methods:

• Installation of perforated curtains in front of laboratory animal cage racks.
• Controlled ventilation system to direct airflow from a corridor through the curtains.
• Collection and analysis of air samples from the corridor and behind curtains for Mus m1 allergen levels.

Main Results:

• Airflow was directed from the corridor through the perforated curtains and racks.
• The curtain system effectively contained allergens behind the curtains.
• Significant reduction in allergen spread from cages into the main animal room aisle was observed.

Conclusions:

• Perforated Makrolon curtains are an efficient method for preventing rodent allergen spread.
• This intervention enhances allergen control within animal facilities.
• The study provides evidence for improved occupational safety through environmental modification.