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Late-onset arrhythmogenic right ventricular cardiomyopathy
Gianfranco Frigo1, Barbara Bauce, Cristina Basso
1Department of Cardiology, University of Padua Medical School, Padua, Italy.
Journal of Cardiovascular Medicine (Hagerstown, Md.)
|April 29, 2006
Summary
Arrhythmogenic right ventricular cardiomyopathy (ARVC) can manifest in older adults, challenging diagnosis. Continued screening is vital for at-risk individuals throughout their lives.
Area of Science:
- Cardiology
- Genetics
- Internal Medicine
Background:
- Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a primary myocardial disease typically diagnosed in younger individuals.
- Classic ARVC diagnosis relies on established clinical and instrumental features.
- Late-onset ARVC presents diagnostic challenges due to left ventricular involvement and potential coronary artery disease.
Observation:
- Two female patients presented with right ventricular morphological and kinetic abnormalities consistent with ARVC in their fifties.
- These cases highlight atypical presentations of ARVC in later adulthood.
Findings:
- ARVC diagnosis in older patients can be complicated by overlapping conditions and atypical disease presentation.
- Morphological and kinetic RV abnormalities indicative of ARVC can emerge in individuals in their fifth decade.
Implications:
- Clinical surveillance for ARVC should extend throughout adult life for at-risk populations.
- Consideration of ARVC in older patients with unexplained ventricular abnormalities is crucial.
- This underscores the importance of lifelong monitoring for inherited cardiomyopathies.
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