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Updated: Aug 9, 2026

Interventional Diagnostic Procedure: A Practical Guide for the Assessment of Coronary Vascular Function
Published on: March 15, 2022
The current and future state of interventional cardiology: a critical appraisal
1Swiss Cardiovascular Center Bern, University Hospital, Bern, Switzerland. bernhard.meier@insel.ch
Insights
Cardiac catheterization procedures, including percutaneous coronary intervention (PCI), are now common. Stenting is the default PCI approach, though its benefit over balloon angioplasty is limited, highlighting research application challenges.
Area of Science:
- Interventional Cardiology
- Cardiovascular Medicine
Background:
- Cardiac catheter-based procedures have evolved significantly over decades.
- Percutaneous coronary intervention (PCI) is now more frequent than coronary artery bypass surgery.
- Stent implantation is the standard PCI approach, despite modest improvements over balloon angioplasty.
Purpose of the Study:
- To analyze the current landscape of cardiac catheter-based interventions.
- To evaluate the application of medical research in interventional cardiology.
- To discuss the future potential of emerging catheter-based procedures.
Main Methods:
- Review of historical trends in invasive and interventional cardiology.
- Analysis of patient data comparing PCI with coronary artery bypass surgery.
- Assessment of the efficacy of stenting versus balloon angioplasty in PCI.
- Discussion of the potential clinical integration of novel catheter-based therapies.
Main Results:
- PCI significantly outnumbers coronary artery bypass surgery.
- Drug-eluting stent implantation offers limited additional benefit in approximately 25% of PCI cases compared to balloon angioplasty.
- Electrophysiological interventions, patent foramen ovale closure, and transcatheter aortic valve replacement show promise for routine use.
Conclusions:
- The widespread adoption of stenting in PCI exemplifies complex research translation in medicine.
- Emerging catheter-based procedures are poised to become standard in cardiac catheterization laboratories.
- Regenerative therapies like stem cell treatments for cardiac conditions remain experimental.
Abstract:
After 75 years of invasive and over 50 years of interventional cardiology, cardiac catheter-based procedures have become the most frequently used interventions of modern medicine. Patients undergoing a percutaneous coronary intervention (PCI) outnumber those with coronary artery bypass surgery by a factor of 2 to 4. The default approach to PCI is the implantation of a (drug-eluting) stent, in spite of the fact that it improves the results of balloon angioplasty only in about 25% of cases. The dominance of stenting over conservative therapy or balloon angioplasty on one hand and bypass surgery on the other hand is a flagrant example of how medical research is digested an applied in real life. Apart from electrophysiological interventions, closure ot the patent foramen ovale and percutaneous replacement of the aortic valve in the elderly have the potential of becoming daily routine procedures in catheterization laboratories around the world. Stem cell regeneration of vessels or heart muscle, on the other hand, may remain a dream never to come true.
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