Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

[Processing of spatial information by hippocampal place cells].

Yan-Fang Zuo¹, Fei Luo, Cai-Lian Cui

¹Neuroscience Research Institute, Peking University, Ministry of Education, Beijing 100083, China.

Sheng Li Ke Xue Jin Zhan [Progress in Physiology]

|May 11, 2006

Summary

Hippocampal place cells form cognitive maps and permanent memory engrams for spatial sites. These signals integrate in the nucleus accumbens to drive goal-directed behaviors via motor circuits.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

A Bibliometric and Visualization Analysis of Mindfulness and Meditation Research from 1900 to 2021.

International journal of environmental research and public health·2021

Same author

Learning Context Restrained Correlation Tracking Filters via Adversarial Negative Instance Generation.

IEEE transactions on neural networks and learning systems·2021

Same author

Which injected antiosteoporotic medication is worth paying for? A cost-effectiveness analysis of teriparatide, zoledronate, ibandronate, and denosumab for postmenopausal osteoporotic women in China.

Menopause (New York, N.Y.)·2021

Same author

Hepatic TM6SF2 Is Required for Lipidation of VLDL in a Pre-Golgi Compartment in Mice and Rats.

Cellular and molecular gastroenterology and hepatology·2021

Same author

Construction and validation of a metabolic gene-associated prognostic model for cervical carcinoma and the role on tumor microenvironment and immunity.

Aging·2021

Same author

A Nanobody-Mediated Virus-Targeting Drug Delivery Platform for the Central Nervous System Viral Disease Therapy.

Microbiology spectrum·2021

Area of Science:

Neuroscience
Cognitive Science
Cellular Biology

Context:

The hippocampus plays a crucial role in spatial memory and navigation.
Understanding the neural circuits underlying memory formation and behavior is essential.

Purpose:

To elucidate the role of hippocampal place cells in creating spatial engrams.
To describe the neural pathway from hippocampal output to goal-directed behavior.

Summary:

Hippocampal place cells process environmental information to establish cognitive maps and synaptic connections, forming permanent memory engrams for specific locations.
Outputs from the hippocampus are integrated within the nucleus accumbens.
This integration ultimately initiates goal-directed behaviors through the motor circuit.

Related Experiment Videos

Impact:

Provides a detailed neural circuit model for spatial memory and behavior.
Highlights the hippocampus's function in memory consolidation and behavioral initiation.
Offers insights into the neural basis of navigation and motivated actions.