Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Critical values in anatomic pathology.

Jan F Silverman1, Telma C Pereira

  • 1Department of Pathology and Laboratory Medicine, Allegheny General Hospital, Pittsburgh, PA 15212, USA. jsilverm@wpahs.org

Archives of Pathology & Laboratory Medicine
|May 11, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Pleural Effusion Cytology of Metastatic Sclerosing Epithelioid Fibrosarcoma.

Diagnostic cytopathology·2026
Same author

Neutrophil Cannibalism by Tumor Cells in Squamous Cell Carcinoma: Cytologic Features and Clinical Implications.

Diagnostic cytopathology·2025
Same author

Diagnostic challenges of the neurofibroma-malignant peripheral nerve sheath tumor spectrum in neurofibromatosis type 1: illustrative case.

Journal of neurosurgery. Case lessons·2025
Same author

Analyzing the impact of molecular testing on the cytological diagnosis of thyroid nodules: Insights from our institution's experience.

Cancer cytopathology·2025
Same author

Fine Needle Aspiration Cytology of Metastatic Endolymphatic Sac Tumor: A Case Report.

Diagnostic cytopathology·2025
Same author

Primary Osseous Low-Grade Myxofibrosarcoma of Clavicle Presenting With Multiple Skeletal Metastases.

Cureus·2020
Same journal

Assessing Human Epidermal Growth Factor Receptor 2 in Urothelial Carcinoma: Insights From Clinical Practice Into Scoring Criteria, Histologic Subtypes, and Genomic Characteristics Across Disease Sites.

Archives of pathology & laboratory medicine·2026
Same journal

Cross-Reactivity of TPIT Antibody Clone OTI2G1 in Chordoma: Structural Mechanisms and Diagnostic Implications.

Archives of pathology & laboratory medicine·2026
Same journal

Paracoccidioidomycosis at Autopsy: A Case Series and Literature Review.

Archives of pathology & laboratory medicine·2026
Same journal

Accuracy of Cytology Diagnosis for Well Differentiated Neuroendocrine Tumors: Assessment by the College of American Pathologists Non-Gynecologic Slide Program.

Archives of pathology & laboratory medicine·2026
Same journal

Serum Immunofixation Electrophoresis Guidance Conflict: A Call to Harmonize.

Archives of pathology & laboratory medicine·2026
Same journal

In Reply.

Archives of pathology & laboratory medicine·2026
See all related articles

Critical values (CVs) in anatomic pathology are uncommon but require immediate physician notification for timely treatment. Establishing clear guidelines for these critical diagnoses is essential for improving patient safety and standardizing care.

Area of Science:

  • Anatomic Pathology
  • Laboratory Medicine
  • Patient Safety

Background:

  • Clinical pathology utilizes critical values (CVs) for urgent physician notification.
  • Anatomic pathology currently lacks established guidelines for critical diagnoses.
  • Patient safety initiatives have increased focus on improving medical error reporting.

Purpose of the Study:

  • To investigate the incidence of CVs in surgical pathology and cytology.
  • To assess pathologist and clinician perceptions regarding CVs in anatomic pathology.
  • To highlight the need for standardized CV guidelines in anatomic pathology.

Main Methods:

  • Retrospective review of surgical pathology reports.
  • Analysis of critical values in cytology.

Related Experiment Videos

  • Survey of pathologist and clinician opinions on CV urgency and management.
  • Main Results:

    • CVs in surgical pathology and cytology are infrequent but occur.
    • Significant variation exists in identifying CV cases and perceived urgency.
    • Lack of consensus among pathologists and clinicians on CV definitions and protocols.

    Conclusions:

    • Anatomic pathology CVs are not rare and necessitate clear management protocols.
    • Developing standardized guidelines for anatomic pathology CVs can enhance patient safety.
    • A community-wide discussion is needed to establish practice-improving CV guidelines.