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Cardiac arrest associated with febrile illness due to U.K. acquired Cyclospora cayetanensis
Christopher Burrell1, Srinivasulu Reddy, Guy Haywood
1Department of Cardiology, Southwest Cardiothoracic Centre, Derriford Hospital, Plymouth PL6 8DH, UK. chris.burrell@phnt.swest.nhs.uk
Insights
A rare Cyclospora cayetanensis infection caused fever and diarrhea, leading to cardiac arrest in a UK man. This case highlights the potential link between febrile illnesses and fatal ventricular arrhythmias.
Area of Science:
- Infectious Diseases
- Cardiology
- Clinical Medicine
Background:
- Cyclospora cayetanensis is an intestinal pathogen causing gastrointestinal illness.
- Febrile illnesses can precipitate cardiac events, particularly ventricular arrhythmias.
Observation:
- A 43-year-old man with UK-acquired Cyclospora cayetanensis infection developed fever and diarrhea.
- During his febrile illness, he experienced an out-of-hospital cardiac arrest.
Findings:
- Extensive cardiac investigations, including echocardiogram, coronary angiogram, and electrophysiological studies, did not reveal an underlying cardiac cause.
- The case suggests a potential association between Cyclospora infection-induced fever and cardiac arrest.
Implications:
- Clinicians should consider the possibility of severe cardiac dysrhythmias in patients with febrile illnesses, even without known cardiac conditions.
- This case underscores the importance of recognizing potential triggers for ventricular arrhythmias during infections.
Abstract:
This report describes a 43 yr old man diagnosed with U.K. acquired cyclospora cayetanensis infection resulting in fever and diarrhoea. In course of the febrile illness, he suffered an out of hospital cardiac arrest. Extensive cardiac investigation including a transthoracic echocardiogram, coronary angiogram, and cardiac electrophysiological studies failed to identify the cause. The possible links between cyclospora infection and cardiac arrest are explored. Fever has been reported as a precipitant for idiopathic ventricular fibrillation in patients with the Brugada syndrome but also rarely in individuals with normal hearts. Clinicians should be aware of a possible link between any febrile illness and potentially fatal ventricular dysrhythmia.
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