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Published on: January 18, 2021
Parkinsonism in Caplan's syndrome
G Rizzo1, C Scaglione, G Lopane
1Department of Neurological Sciences, University of Bologna, Via Ugo Foscolo 7, I-40123 Bologna, Italy.
Abstract:
Parkinsonism is a rare feature of immunological diseases. We describe a 67-year-old man with Caplan's syndrome (CS) and parkinsonism. CS is an immunologic disease characterised by the presence of rheumatoid arthritis associated with a specific form of pneumoconiosis. Parkinsonism as a manifestation of involvement of the central nervous system in this condition has never been reported. Following immunosuppressive treatment both the CS and the parkinsonian signs and symptoms showed a marked improvement. The role of immune mechanisms in these parkinsonian syndromes is discussed.
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