Peculiarities of lipid profile parameters in cardiac patients with hypo- and hyperthyroidism

Area of Science:

• Cardiology
• Endocrinology
• Clinical Biochemistry

Background:

• Thyroid dysfunction is a prevalent issue in cardiac patients.
• Cardiovascular disease is common among individuals with thyroid disorders.

Purpose of the Study:

• To assess lipid profile variations in cardiology patients with hypothyroidism, hyperthyroidism, and normal thyroid function.
• To investigate the relationship between thyroid status and atherogenic lipid fractions.

Main Methods:

• Evaluated 73 cardiology patients with varying thyroid function (hypo-, hyper-, euthyroid).
• Assessed lipid profile parameters including total cholesterol, LDL, HDL, and triglycerides.
• Diagnosed thyroid dysfunction using clinical status and thyroid-stimulating hormone levels.

Main Results:

• Hypothyroid patients exhibited elevated total cholesterol, LDL cholesterol, and triglycerides.
• Hyperthyroid patients generally showed normal lipid concentrations.
• High-density lipoprotein cholesterol levels were normal across all thyroid function groups.
• The most atherogenic lipid profiles were observed in hypothyroid patients with co-existing diabetes mellitus.

Conclusions:

• Thyroid dysfunction, particularly hypothyroidism, is linked to adverse changes in atherogenic lipid profiles.
• Thyroid dysfunction may independently contribute to dyslipidemia in cardiac patients.
• Managing thyroid status is crucial for optimizing lipid profiles in cardiovascular care.