[Changes of blood paramagnetic centres of animals irradiated with low-intensity laser]

Therapeutic effects of lasers are based on activation of oxidative process on cellular and subcellular levels. The first photoacceptor of laser beam being mitochondria., which simultaneously represents the source of oxidation products as well as their target and thus, laser exposure can cause numerical effects: inactivation of electron chain components of mitochondria, energy metabolism inhibition, oxidation of lipids and DNA molecule. The aim of the given work is to investigate the influence of submaximal dozes of infrared (0,85 mkm) low-intensity laser on the activity of oxidative processes in laboratory mice blood, which are reflected on the state of paramagnetic centers. For this purpose the condition of blood paramagnetic centers (caeruloplazmin, Fe(3+)-transferin, Fe(2+), Mn(2+), MetHb and NO) has been studied. Results imply that irradiation of mice blood with submaximal dozes of low-intensity laser causes the activation of oxidative process, but those changes do not lead to impairment of blood antioxidant features.