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Updated: Aug 8, 2026

Cell-Free DNA Extraction of Vitreous and Aqueous Humor Specimens for Diagnosis and Monitoring of Vitreoretinal Lymphoma
Published on: January 12, 2024
[Orbital MALT lymphomas: clinicopathological correlation]
B Schröder-Frei1, M Kurrer, K Chaloupka
1Universitäts-Augenklinik, Zürich. bettina.schroeder@usz.ch
Background:
Extranodal MALT lymphomas are slow growing tumors of B-cell origin which may be found in the orbit. They are associated with mucosa and epithelial structures.
Patients And Methods:
We present eight patients with biopsy confirmed orbital MALT Lymphomas. The diagnostic imaging techniques are described. Histopathological and immunohistological analysis showed typical findings of MALT lymphomas.
Results:
After staging six patients had radiation therapy. Two patients refused treatment due to lack of discomfort.
Conclusions:
MALT lymphomas should be considered in the differential diagnosis of orbital tumors. While ultrasonography and MRI are needed to determine the extension of these tumors, their identification requires excision or biopsy with histological/immunohistochemical analysis, especially in view of new treatment options.
