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Updated: Aug 8, 2026

Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors
Published on: September 20, 2016
[ENT cancers and genomics]
1Laboratoire d'Oncopharmacologie, CRLCC de Nice, Centre Antoine-Lacassagne, France.
Abstract:
ENT cancers in France - with the fourth rank after the breast, colon and prostate localizations - represent on important problem of public health. Survival at five years reaches a maximum in spite of undeniable therapeutic progress, in particular with the targeted treatments associated to conventional cytotoxic drugs. The studies in progress still make it possible to hope for new predictive and prognostic biological markers, but the complexity of these parameters, as well as the needs for heavy and expensive equipment to explore them, require a unification of the efforts and means. It is the major objective of the cooperative program PACOR.
Insights
Head and neck cancers are a significant public health issue in France. The PACOR program aims to unify research efforts for better predictive and prognostic markers, improving patient survival despite therapeutic advancements.
Area of Science:
- Oncology
- Public Health
- Biomarker Research
Context:
- Ear, Nose, and Throat (ENT) cancers rank fourth in incidence in France, posing a significant public health challenge.
- Despite therapeutic progress, including targeted therapies and cytotoxic drugs, five-year survival rates for ENT cancers remain a concern.
- Current research seeks novel predictive and prognostic biological markers for ENT cancers.
Purpose:
- To address the complexity and resource demands of identifying new biological markers for ENT cancers.
- To unify research efforts and resources through the cooperative program PACOR.
- To improve the understanding and management of ENT cancers.
Summary:
- The PACOR program focuses on unifying research for ENT cancer biomarkers.
- It aims to overcome the complexity and cost associated with exploring new predictive and prognostic markers.
- This collaborative effort seeks to enhance therapeutic strategies and patient outcomes.
Impact:
- Facilitate the discovery of new, reliable biomarkers for ENT cancers.
- Promote a unified approach to cancer research, optimizing resource allocation.
- Ultimately improve survival rates and patient prognosis for head and neck cancers.
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