Related Experiment Video
Updated: Aug 8, 2026

Oral Gavage in Neonatal Mouse Pups and Functional Assessment of Gut Barrier Integrity Using Ussing Chambers
Published on: January 9, 2026
Functional foods and paediatric gastro-intestinal health and disease
C J Taylor1, E Mahenthiralingam
1Department of Paediatric Gastroenterology, University of Sheffield, UK. c.j.taylor1@sheffield.ac.uk
Abstract:
The application of molecular methods to gastro-intestinal diseases is giving insight into the way in which the resident intestinal microbiota interacts with the mucosal immune system. Using traditional culture techniques, the importance of mucosally-associated bacterial biofilms in maintaining mucosal integrity has been demonstrated in ways previously impossible. Changes in the balance of organisms at initiation of and during disease provide a rationale for interventions with functional foods which facilitate re-establishment of the homeostasis of healthy gut.
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