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Heterodimeric, disulfide-linked alpha/beta T cell receptors in solution

A E Slanetz1, A L Bothwell

  • 1Department of Biology, Yale University School of Medicine, New Haven, CT 06510.

European Journal of Immunology
|January 1, 1991
PubMed
Summary

Researchers developed a soluble T cell receptor (TcR) by linking its extracellular domains to a Thy-1 anchor. This soluble TcR retains its native conformation, aiding structural and functional studies of TcR-ligand interactions.

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