Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Testosterone treatments: why, when, and how?

Katherine Margo1, Robert Winn

  • 1Department of Family Practice and Community Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA. margok@uphs.upenn.edu

American Family Physician
|May 25, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

BPI26-022: Reducing Diagnosis-to-Treatment Times in Cancer Care: A Community-Engaged Approach to Health Equity.

Journal of the National Comprehensive Cancer Network : JNCCN·2026
Same author

QIM26-291: Advancing Health Equity in Cancer Care Through Social Drivers of Health Integration.

Journal of the National Comprehensive Cancer Network : JNCCN·2026
Same author

QIM26-291: Advancing Health Equity in Cancer Care Through Social Drivers of Health Integration.

Journal of the National Comprehensive Cancer Network : JNCCN·2026
Same author

BPI26-022: Reducing Diagnosis-to-Treatment Times in Cancer Care: A Community-Engaged Approach to Health Equity.

Journal of the National Comprehensive Cancer Network : JNCCN·2026
Same author

Functional Dynamics of Arginine Mono- and Di-Methylation.

Cells·2025
Same author

Ovarian tumor cells gain competitive advantage by actively reducing the cellular fitness of microenvironment cells.

Nature biotechnology·2024
Same journal

For Post-stent Patients With Atherosclerotic Coronary Vascular Disease Who Are Taking an Anticoagulant, Adding Aspirin Worsens Outcomes.

American family physician·2026
Same journal

Nausea and Vomiting During Pregnancy.

American family physician·2026
Same journal

Metabolic Dysfunction-Associated Steatotic Liver Disease: Diagnosis and Management.

American family physician·2026
Same journal

Aerobic Exercise Is the Better Exercise Modality for Knee Osteoarthritis.

American family physician·2026
Same journal

Overscreening Leads to Overdiagnosis of MASLD.

American family physician·2026
Same journal

Type 2 Diabetes: Outpatient Insulin Management.

American family physician·2026
See all related articles

Testosterone therapy is increasingly prescribed for sexual dysfunction and other conditions, despite limited long-term safety data. Potential benefits like improved libido and well-being exist, but risks and monitoring are crucial.

Area of Science:

  • Endocrinology
  • Pharmacology
  • Men's and Women's Health

Background:

  • Testosterone treatment is increasingly common, particularly for sexual dysfunction and menopausal symptoms.
  • Long-term outcome data for testosterone therapy remain limited, raising concerns about its widespread use.
  • Current applications include treating sexual dysfunction in both sexes and hot flashes in women.

Purpose of the Study:

  • To review the current uses, benefits, and risks of testosterone therapy.
  • To highlight the need for ongoing research into long-term effects.
  • To inform clinical practice regarding monitoring and potential side effects.

Main Methods:

  • Literature review of existing studies on testosterone therapy.
  • Analysis of reported benefits, such as improved libido, bone mass, and mood.

Related Experiment Videos

  • Examination of documented side effects in men and women.

    • Main Results:

    • Testosterone therapy can improve libido, bone mass, mood, and energy levels.
    • Side effects in men include polycythemia and acne; in women, acne, hepatotoxicity, and virilization (at high doses).
    • Long-term effects on prostate cancer, breast cancer, and cardiovascular disease are not yet fully understood.

    Conclusions:

    • Testosterone therapy offers potential benefits but carries risks that necessitate careful patient selection and monitoring.
    • Further long-term studies are essential to fully evaluate the safety and efficacy of testosterone treatment.
    • Monitoring of hematocrit, lipids, and cancer markers (PSA, mammograms) is recommended for patients on testosterone therapy.