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Updated: Aug 8, 2026

"Liver-on-a-Chip" Cultures of Primary Hepatocytes and Kupffer Cells for Hepatitis B Virus Infection
Published on: February 19, 2019
[Chronic viral diseases of the liver and oncoproteins externalization in hepatocytes]
Luigi Santacroce1, Tommaso Losacco
1Dipartimento di Odontostomatologia e Chirurgia (DOC), Cattedra di Chirurgia Generale, Università, Bari.
Abstract:
Strong interest exists about the biomolecular basis of the chronic liver diseases due to viral infections. It seems to be very interesting because of their evolutive potential. In this context the study of oncogenes and oncoproteins could be interesting as prognostic factors for chronic viral diseases of the liver. In this study the authors show the results obtained about EGF and p62 expression in 39 selected patients with cirrhosis and 3 different chronic viral hepatitis (persistent, lobular, and active).
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