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The Multiple Sclerosis Performance Test (MSPT): An iPad-Based Disability Assessment Tool
Published on: June 30, 2014
Multimodal evoked potentials to assess the evolution of multiple sclerosis: a longitudinal study
L Leocani1, M Rovaris, F M Boneschi
1Department of Neurology, Clinical Neurophysiology and Neurorehabilitation, Scientific Institute Hospital San Raffaele, University Vita-Salute, Milan, Italy. leocani.letizia@hsr.it
Journal of Neurology, Neurosurgery, and Psychiatry
|June 1, 2006
Summary
Evoked potentials effectively measure nervous system damage severity in multiple sclerosis. These results indicate evoked potentials can predict future disability progression in multiple sclerosis patients.
Area of Science:
- Neuroscience
- Clinical Neurology
- Biomedical Engineering
Background:
- Evoked potentials assess sensory and motor pathway function.
- Their role in monitoring multiple sclerosis (MS) evolution requires further clarification.
Purpose of the Study:
- To evaluate multimodal evoked potentials for predicting MS disease severity.
- To determine the prognostic value of evoked potentials in MS.
Main Methods:
- Eighty-four MS patients underwent Expanded Disability Status Scale (EDSS) and functional system scoring.
- Multimodal evoked potentials were recorded at baseline and follow-up.
- Evoked potential scores were quantified using a conventional scoring system.
Main Results:
- Evoked potential scores correlated significantly with functional system scores and EDSS.
- Baseline evoked potential scores were more severe in patients with subsequent disability progression.
- Severe baseline global evoked potential scores increased the risk of disability progression by 72.5%.
Conclusions:
- Evoked potentials serve as reliable markers for nervous system damage severity in MS.
- Evoked potentials demonstrate predictive value for disability evolution in multiple sclerosis.
