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Peptide-based Identification of Functional Motifs and their Binding Partners
Published on: June 30, 2013
Acute rheumatic fever in human immunodeficiency virus infection
K W Radcliffe1, K A McLean, A G Benbow
1Department of Genitourinary Medicine, Charing Cross Hospital, London, U.K.
Abstract:
A 25-year-old homosexual man with a childhood history of rheumatic heart disease presented with painful joints, fever and chest pain. He was diagnosed as having acute rheumatic fever and was found to be HIV antibody-positive. His illness responded to conventional treatment but he had a persistently low CD4 lymphocyte count and was started on zidovudine. Interpretation of the significance of a low CD4 lymphocyte count is problematic in a patient with coincident rheumatic fever and HIV infection as both conditions can cause CD4 lymphopenia.
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