Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Mucosal restitution].

Byung Chul Yoon1

  • 1Division of Gastroenterology, Department of Internal Medicine, Hanyang University Medical Center, Seoul, Korea. yoonbc@hanyang.ac.kr

The Korean Journal of Gastroenterology = Taehan Sohwagi Hakhoe Chi
|July 1, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Toward Foundational Model for Sleep Analysis Using a Multimodal Hybrid-Self-Supervised Learning Framework.

IEEE transactions on cybernetics·2025
Same author

Improving real-time ultrasound spine imaging with a large-aperture array.

Science advances·2025
Same author

Recurrent Coronary Artery Vasospasm in a Patient with Hepatocellular Carcinoma Treated with Sorafenib: a Case Report and Literature Review.

Journal of liver cancer·2023
Same author

Prevalence and clinical characteristics of antibiotics associated drug induced liver injury.

Annals of translational medicine·2021
Same author

Rates and Risk Factors for Interval Gastric Cancers at Screening Gastroscopy.

The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology·2021
Same author

Correlation between Three-Dimensional Volume and Malignant Potential of Gastrointestinal Stromal Tumors (GISTs).

Journal of clinical medicine·2020
Same journal

Macro-Aspartate Aminotransferase Elevation in a Patient with Chronic Hepatitis B.

The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi·2026
Same journal

Fatal Clinical Course of Hepatic Portal Venous Gas Associated with Thrombosed Abdominal Aortic Aneurysm.

The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi·2026
Same journal

Risk Factors for Adverse Circulatory and Respiratory Events in Patients Undergoing Esophageal Endoscopic Submucosal Dissection Under Dexmedetomidine-Based Sedation.

The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi·2026
Same journal

[Achievements and Future Directions of the National Colorectal Cancer Screening Program in Korea].

The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi·2026
Same journal

[Advanced Combination Therapy in Inflammatory Bowel Disease].

The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi·2026
Same journal

[Immunotherapy and Targeted Therapy for Advanced Biliary Tract Cancer].

The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi·2026
See all related articles

Intestinal repair begins with restitution, where cells move to cover wounds without dividing. This process involves cell shape changes and interactions with the extracellular matrix, offering therapeutic targets for gut healing.

Area of Science:

  • Gastroenterology and Cell Biology
  • Focuses on the cellular mechanisms of intestinal repair and epithelial regeneration.

Context:

  • Superficial intestinal epithelial damage triggers a repair process called restitution.
  • Restitution involves the migration of adjacent epithelial cells to cover the wounded area.
  • This process occurs without cell proliferation.

Purpose:

  • To elucidate the cellular and molecular mechanisms underlying intestinal restitution.
  • To identify key signaling pathways and molecular interactions regulating epithelial cell migration during wound repair.
  • To explore therapeutic strategies for enhancing gastrointestinal wound healing.

Summary:

  • Intestinal repair initiates with restitution, a process of cell migration over damaged areas, distinct from proliferation.

Related Experiment Videos

  • Epithelial-mesenchymal transition (EMT) is crucial for cell motility, regulated by intracellular signaling and actin cytoskeleton dynamics.
  • Integrin-mediated cell-matrix interactions and various cytokines/growth factors modulate restitution.

    • Impact:

    • Understanding restitution provides insights into potential therapeutic interventions for gastrointestinal disorders.
    • This knowledge can guide the development of treatments to accelerate or improve gut wound healing.
    • Identifies key molecular players for future drug development in regenerative medicine for the gut.