Chromosome aberrations in solid tumors have a stochastic nature

Mauro A A Castro1, Tor G H Onsten, José C F Moreira

  • 1Departamento de Bioquímica, Universidade Federal do Rio Grande do Sul, Rua Ramiro Barcelos 2600-anexo, Porto Alegre 90035-003, Brazil. mauro@ufrgs.br <mauro@ufrgs.br>

Mutation Research
|July 4, 2006
PubMed
Summary

Chromosome aberrations in cancer are neither fully random nor deterministic. Their spread, quantified using Shannon information, correlates with tumor type and survival, suggesting recurrence indicates better prognosis.

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