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Updated: Aug 7, 2026
09:32
Network Analysis of Foramen Ovale Electrode Recordings in Drug-resistant Temporal Lobe Epilepsy Patients
Published on: December 18, 2016
Epilepsy surgery for the neurocutaneous disorders
Adam L Hartman1, Eric H Kossoff
1Johns Hopkins Medical Institutions, Baltimore, MD 21287-1000, USA.
Seminars in Pediatric Neurology
|July 5, 2006
Summary
Neurophakomatoses patients can now undergo surgical resection for epilepsy. Advances in surgical techniques and imaging allow for better seizure control through targeted removal of active brain areas.
Area of Science:
- Neurology
- Neurosurgery
- Epileptology
Background:
- Neurophakomatoses often present multifocal disease, complicating epilepsy surgery candidacy.
- Historically, surgical resection for epileptogenic foci in these patients was limited.
Purpose of the Study:
- To explore the evolving role of surgical resection in managing epilepsy associated with neurophakomatoses.
- To highlight advancements enabling surgical intervention for improved seizure control.
Main Methods:
- Review of recent advances in neuroimaging and epilepsy monitoring.
- Analysis of surgical techniques for focal and hemispheric resections.
- Evaluation of patient selection criteria for neurophakomatoses-related epilepsy surgery.
Main Results:
- Improved identification of highly active epileptogenic foci is now possible.
- Surgical options have expanded from focal resections to hemispherectomies.
- These interventions offer potential for better seizure control than medication alone.
Conclusions:
- Surgical resection is an increasingly viable option for neurophakomatoses patients with epilepsy.
- Advancements in technology and surgical approaches enhance treatment efficacy.
- Tailored surgical strategies can lead to significant seizure reduction.
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