Related Experiment Video
Updated: Aug 7, 2026

A High-throughput Platform for the Screening of Salmonella spp./Shigella spp.
Published on: November 7, 2018
[Etiology of community - acquired acute diarrhea in children]
Agnieszka Szlagatys-Sidorkiewicz1, Julianna Kurlenda, Anna Liberek
1Klinika Pediatrii, Gastroenterologii i Onkologii Dzieciecej, Akademia Medyczna, ul. Nowe Ogrody 1-6, 80-803 Gdansk, Poland. aga1@amg.gda.pl
Insights
Rotavirus is the most common cause of acute diarrhea in children, identified in over half of diagnosed cases. Bacterial infections like salmonellosis were also found, with rotavirus more prevalent in girls and bacterial causes in boys.
Area of Science:
- Pediatric infectious diseases
- Gastroenterology
- Microbiology
Context:
- Community-acquired acute diarrhea is a common pediatric illness.
- Etiological diagnosis is crucial for effective treatment and prevention.
- Current diagnostic methods may not identify all causative agents.
Purpose:
- To analyze the etiology of acute diarrhea in children.
- To determine the prevalence of specific pathogens including rotavirus, adenovirus, Salmonella, and EPEC.
- To compare demographic and seasonal patterns of different diarrhea types.
Summary:
- Rotavirus was the most frequent cause of acute diarrhea in children (24.67%), followed by Salmonella (7.06%) and EPEC strains (A, B, C).
- Etiology was identified in 43.6% of cases, with rotavirus being the most common diagnosis.
- Bacterial diarrhea was more prevalent in boys and rotaviral diarrhea in girls, with rotavirus peaking in spring.
Impact:
- Highlights the significant role of rotavirus in pediatric acute diarrhea.
- Suggests that current diagnostic approaches are insufficient for comprehensive etiological determination.
- Recommends expanding diagnostic testing for acute diarrhea in children to improve patient outcomes.
The Aim:
of the study was to analyse the etiology of home acute diarrhea in children.
Material And Methods:
2636 children with community-acquired acute diarrhea were included in the study. Stool samples were analysed for the presence of Salmonella spp, Shigella spp, rotaviruses and adenoviruses.
Results:
etiology of acute diarrhea was established in 1149 out of 2636 children (43.6%). Among the children with known etiology - rotaviral diarrhea was most frequently diagnosed (24.67%), whereas salmonellosis - in 7.06% of cases, EPEC C - 6.37%, EPEC B - 2.92%, EPEC A - 1.89%, adenoviral diarrhea in 0.68%. Mean age of children with bacterial acute diarrhea (Salmonella, EPEC A, B, C) was higher as compared to the mean age of children with rotaviral acute diarrhea (p < 0.002). Rotaviral acute diarrhea was more frequently diagnosed in girls (p < 0.025), whereas bacterial - in boys (p < 0.044). The highest prevalence of acute rotaviral diarrhea was found in winter/spring, with peak in April.
Conclusions:
commonly used diagnostic procedure does not allow to establish the etiology of acute home diarrhea in children in most cases. Rotavirus is found in the majority of diagnosed cases. It seems reasonable to expand the spectrum of diagnostic tests in cases of acute diarrhea in children.
Related Concept Videos
Drugs Affecting GI Tract Motility: Antimicrobials as Antidiarrheal Agents
Bacterial Gastroenteritis
Giardiasis
Cholera
Amebiasis
Inflammatory Bowel Disease I: Ulcerative Colitis
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
