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Updated: Aug 7, 2026

Granulocyte-dependent Autoantibody-induced Skin Blistering
Published on: October 12, 2012
A novel case of polyfibromatosis and interstitial granulomatous dermatitis with arthritis
Daniel Litu Chen1, Alvin H Chong, Jack Green
1Department of Dermatology, St Vincent's Hospital, Melbourne, Australia.
Abstract:
Polyfibromatosis is a rare condition in which several cutaneous fibrotic conditions, such as Dupuytren's contracture, keloid formation, Peyronie's disease and plantar fibromatosis, may coexist. Interstitial granulomatous dermatitis with arthritis is also a rare condition characterized by arthritis and infiltrated rope-like lesions with granulomatous histologic features. We report a case of the simultaneous occurrence of both conditions in the same individual. To our knowledge, this has not been previously described. The clinical course has been slow, progressive, and recalcitrant to treatment.
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