Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Optimized 1D double quantum filter NMR experiments.

V Ramesh1, N Chandrakumar

  • 1Department of Chemistry, Indian Institute of Technology-Madras, Chennai-600 036, Tamil Nadu, India.

Magnetic Resonance in Chemistry : MRC
|July 21, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

<sup>1</sup>H NMR with Partial Transition Selectivity.

The journal of physical chemistry. A·2022
Same author

Assessment of the Role of 2,2,2-Trifluoroethanol Solvent Dynamics in Inducing Conformational Transitions in Melittin: An Approach with Solvent <sup>19</sup>F Low-Field NMR Relaxation and Overhauser Dynamic Nuclear Polarization Studies.

The journal of physical chemistry. B·2020
Same author

Motional Dynamics of Halogen-Bonded Complexes Probed by Low-Field NMR Relaxometry and Overhauser Dynamic Nuclear Polarization.

Chemistry, an Asian journal·2019
Same author

Blaschkoid distribution of composite syringocystadenoma papilliferum and tubular apocrine adenoma without naevus sebaceous.

Clinical and experimental dermatology·2018
Same author

Asymptomatic indurated plaque on the tongue in an immunocompetent man.

International journal of dermatology·2018
Same author

Revisiting the role of the slit-skin smear in the diagnosis of Indian post-kala-azar dermal leishmaniasis.

Indian journal of dermatology, venereology and leprology·2018
Same journal

Interaction With Surface Spins as a Contribution to Nuclear Magnetic Relaxation of Liquids Adsorbed in Mesoporous Materials.

Magnetic resonance in chemistry : MRC·2026
Same journal

Complexation Process of Pravastatin With Metal Ions (Gadolinium, Nickel, Zinc) by NMR Spectroscopy.

Magnetic resonance in chemistry : MRC·2026
Same journal

<sup>17</sup>O Quadrupole Coupling Constants in Water.

Magnetic resonance in chemistry : MRC·2026
Same journal

Photochemical Pump, Benchtop NMR Probe Spectroscopy for Reaction Monitoring With paraHydrogen.

Magnetic resonance in chemistry : MRC·2026
Same journal

Pulse Programme Considerations for Quantitative NOE Analysis.

Magnetic resonance in chemistry : MRC·2026
Same journal

Assessment of Cryogen-Free NMR as Process Analytical Technology for Chemical Process Understanding Across Field Strengths.

Magnetic resonance in chemistry : MRC·2026
See all related articles

We developed a new 1D pulse sequence for efficient conversion of double quantum coherence (DQC), enhancing sensitivity and bandwidth for nuclear magnetic resonance (NMR) spectroscopy. This method improves chemical shift and coupling information retrieval in complex systems.

Area of Science:

  • Nuclear Magnetic Resonance (NMR) Spectroscopy
  • Quantum Coherence Manipulation
  • Solid-State and Solution-State Chemistry

Background:

  • Double Quantum Coherence (DQC) is crucial for NMR spectroscopy, but its efficient conversion remains a challenge.
  • Existing reconversion strategies often face limitations in sensitivity and bandwidth.
  • Accurate acquisition of chemical shift and coupling information is vital for molecular structure elucidation.

Purpose of the Study:

  • To propose and demonstrate a novel 1D pulse sequence for optimal efficiency in converting y-phase DQC.
  • To enhance the high-sensitivity bandwidth relative to coupling compared to existing methods.
  • To enable acquisition of comprehensive spectral information, including chemical shifts and couplings, from complex spin systems.

Main Methods:

Related Experiment Videos

  • Development of a 1D pulse sequence utilizing single transition selection for DQC conversion.
  • Implementation of a modified sequence to retrieve chemical shift and coupling data.
  • Application of the sequence to 1D Carbon-13 (13C) INADEQUATE experiments.
  • Testing the sequence on quadrupole coupled spin-1 systems, specifically Deuterium (2H) in lyotropic phases.
  • Optimization of pulse flip angles considering relaxation effects for performance tuning.

Main Results:

  • The proposed 1D pulse sequence achieves optimal efficiency in DQC conversion.
  • The sequence exhibits a larger high-sensitivity bandwidth concerning coupling compared to other reconversion strategies.
  • A modified version successfully recovers chemical shift and coupling information with minimal sensitivity loss.
  • Successful application demonstrated for 1D 13C INADEQUATE and 2H NMR spectroscopy.
  • Sequence performance is tunable via pulse flip angle optimization and consideration of relaxation.

Conclusions:

  • The novel 1D pulse sequence offers an efficient and sensitive method for DQC conversion in NMR.
  • This technique expands the applicability of DQC-based NMR to a broader range of systems, including spin-1 nuclei.
  • The ability to obtain both DQC and direct spectral information enhances structural analysis capabilities.