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Published on: January 22, 2021
FOLFOX4 in advanced colorectal cancer: a monoinstitutional experience
Giorgia Boscolo1, Lara Maria Pasetto, Antonio Jirillo
1Operative Unit of Medical Oncology, Istituto Oncologico Veneto, Padua, Italy.
Aims And Background:
Patients included in clinical trials are "selected", and they usually differ from those commonly treated.
Methods:
From 1999 to 2004, in the Medical Oncology Department of Padua (Italy), 70 metastatic colorectal cancers were treated with FOLFOX4.
Results:
Our results, compared with those of the registration trial (response rate, duration of response and progression-free survival) appeared lower; overall survival was improved.
Conclusions:
The number of therapeutic regimens more than their type influenced the results.
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