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Primary Tumor and MEF Cell Isolation to Study Lung Metastasis
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Published on: May 20, 2015

Genotype-phenotype relationships in a mouse model for human small-cell lung cancer

J Calbó1, R Meuwissen, E van Montfort

  • 1Division of Molecular Genetics and Centre of Biomedical Genetics, The Netherlands Cancer Institute, Amsterdam.

Cold Spring Harbor Symposia on Quantitative Biology
|July 28, 2006
PubMed
Summary

Small-cell lung cancer (SCLC) tumors can contain genetically diverse cells. L-myc amplification and Ascl-1 expression are linked to neuroendocrine SCLC cell populations, potentially influencing metastasis and chemoresistance.

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