Related Experiment Video
Updated: Aug 6, 2026

Using a 1064-nm Picosecond Neodymium-Doped Yttrium Aluminum Garnet Laser for Periorbital Hyperpigmentation
Published on: May 23, 2025
Treatment of vitiligo using the 308-nm excimer laser
Suhail Hadi1, Patricia Tinio, Khalid Al-Ghaithi
1Department of Dermatology, Mount Sinai School of Medicine, New York, New York 10029, USA. Suhail.Hadi@mssm.edu
Objective:
The aim of this study was to study the effectiveness of the 308-nm xenon chloride excimer laser in the treatment of vitiligo and to determine factors that favor a good response to treatment.
Background Data:
Targeted phototherapy using the 308-nm xenon chloride excimer laser represents an effective therapy for the management of vitiligo. However, studies on a large number of patients are few despite the increasing use of the excimer laser to treat patients with vitiligo.
Methods:
A retrospective chart review of 97 patients with chronic stable vitiligo was done with a total of 221 vitiligo patches treated.
Results:
Out of 221 vitiligo patches treated, 50.6% showed 75% pigmentation or more, 25.5% achieved 100% pigmentation of their patches, and 64.3% showed 50% pigmentation or more. Lesions on the face responded better than lesions elsewhere.
Conclusion:
The 308-nm xenon chloride excimer laser is an effective and safe modality for the treatment of vitiligo, with good results achieved in a relatively short duration of time.
