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Psychiatric presentation of voltage-gated potassium channel antibody-associated encephalopathy. Case report
U D Parthasarathi1, T Harrower, M Tempest
1Cambridgeshire & Peterborough Mental Health NHS Trust, Cambridge, UK. upartha@hotmail.co.uk
Abstract:
Voltage-gated potassium channel antibody encephalopathy, a rare cause of limbic encephalopathy, typically presents with memory impairment and seizures. Psychiatric symptoms have not been emphasised in the literature. Here we describe a 58-year-old man who presented with panic attacks and psychogenic non-epileptic seizures and, later on, developed delusions and hallucinations and then confusion. He was found to have antibodies to voltage-gated potassium channels. Treatment with immuno-modulatory therapy resulted in almost complete recovery.
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