Antiinflammatory activity and acute toxicity of Dodonaea viscosa
N M Khalil1, J S Sperotto, M P Manfron
1Department of Pharmacy and Biochemistry, UFVJM, Rua da Glória 187, Diamantina/MG, 39100-000, Brazil. najeh@universia.com.br
Fitoterapia
|August 4, 2006
Abstract:
The hydroalcoholic extract (HAE) of the leaves of Dodonaea viscosa, given by oral route at dose of 300 mg/kg, significantly inhibited the paw edema induced by carrageenin injection. The extract did not show any sign of toxicity in mice up to 5000 mg/kg p.o. This result seems to support the use of D. viscosa leaves ethanolic extract in relieving inflammation.
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