[Inborn bacterial infections during neonatal period]

Considering the high mortality and serios morbilidy associatent with neonatal infections. A competent diagnostic marker also needs to have reasonably high specificity. Good evidence exists to support the use of CRP measurements in conjunction with other established diagnostic tests (such as a white blood cell (WBC) count with differential and blood culture) to establish or exclude the diagnosis of sepsis in full-term or near-term infants. Sepsis was suspected within the first 3 days after birth in. There were 20% early-onset and 53% late-onset episodes of proven sepsis. CRP had sensitivities of 39.4% and 64.6% for proven or probable sepsis and 35.0% and 61.5% for proven sepsis in early-onset and late-onset episodes, respectively. To compare the clinical informative value of and C-reactive protein (CRP) plasma concentrations in the detection of infection and sepsis and in the assessment of severity of sepsis. PCT is a better marker of sepsis than CRP. The course of PCT shows a closer correlation than that of CRP with the severity of infection and organ dysfunction. Diagnostic markers are useful indicators of neonatal bacterial infections C-reactive protein (CRP), procalcitonin (PCT) Intralevcin 6, 8 are early sensitive markers of infection.