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Impulsivity and BOLD fMRI activation in MDMA users and healthy control subjects
Ignacio H Valdes1, Joel L Steinberg, Ponnada A Narayana
1Department of Psychiatry and Behavioral Sciences, University of Texas Health Science Center at Houston, 1300 Moursund, Houston, TX 77030, USA. ivaldes@hal-pc.org
Abstract:
The correlation between scores on the Barratt Impulsiveness Scale (BIS) and activation measured by functional magnetic resonance imaging in a dorsolateral prefrontal cortical (DLPFC) activating task was examined in 15 MDMA-using subjects and 19 controls. A significant correlation between BIS scores and DLPFC activation was found, supporting a role for the DLPFC in BIS-measured impulsivity.
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