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Facile Preparation of (2Z,4E)-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate
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Published on: June 21, 2017

Ruthenium-catalyzed alkylative lactonization and carbocyclization

Barry M Trost1, Andrew McClory

  • 1Department of Chemistry, Stanford University, Stanford, California 94305, USA. bmtrost@stanford.edu

Organic Letters
|August 11, 2006
PubMed
Summary

A novel ruthenium complex catalyzes the efficient synthesis of valuable lactones from allene carboxylic acids and olefins. This mild reaction tolerates diverse functional groups, enabling broader synthetic applications.

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